| Difficult Run to Ashtabula (Ohio) | 274.45 mi (441.68 km) |
| Difficult Run to Ashwaubenon (Wisconsin) | 674.15 mi (1,084.94 km) |
| Difficult Run to Aspen Hill (Maryland) | 19.39 mi (31.21 km) |
| Difficult Run to Astoria (Oregon) | 2,382.47 mi (3,834.21 km) |
| Difficult Run to Atascadero (California) | 2,374.69 mi (3,821.70 km) |
| Difficult Run to Atascocita (Texas) | 1,186.09 mi (1,908.82 km) |
| Difficult Run to Atchison (Kansas) | 951.62 mi (1,531.49 km) |
| Difficult Run to Athens (Alabama) | 601.94 mi (968.72 km) |
| Difficult Run to Athens (Georgia) | 478.40 mi (769.91 km) |
| Difficult Run to Athens (Ohio) | 256.39 mi (412.61 km) |
| Difficult Run to Athens (Tennessee) | 464.80 mi (748.02 km) |
| Difficult Run to Athens (Texas) | 1,134.71 mi (1,826.13 km) |
| Difficult Run to Atlanta (Georgia) | 529.91 mi (852.80 km) |
| Difficult Run to Atlantic Beach (Florida) | 635.08 mi (1,022.06 km) |
| Difficult Run to Atlantic City (New Jersey) | 158.58 mi (255.21 km) |
