| Difficult Run to Allison Park (Pennsylvania) | 180.58 mi (290.61 km) |
| Difficult Run to Allouez (Wisconsin) | 671.23 mi (1,080.24 km) |
| Difficult Run to Aloha (Oregon) | 2,341.98 mi (3,769.05 km) |
| Difficult Run to Alpena (Michigan) | 528.61 mi (850.72 km) |
| Difficult Run to Alpharetta (Georgia) | 509.11 mi (819.33 km) |
| Difficult Run to Alpine (California) | 2,228.16 mi (3,585.88 km) |
| Difficult Run to Alpine (Utah) | 1,822.10 mi (2,932.39 km) |
| Difficult Run to Alsip (Illinois) | 579.60 mi (932.77 km) |
| Difficult Run to Altadena (California) | 2,268.27 mi (3,650.43 km) |
| Difficult Run to Altamont (Oregon) | 2,314.62 mi (3,725.02 km) |
| Difficult Run to Altamonte Springs (Florida) | 744.51 mi (1,198.17 km) |
| Difficult Run to Alton (Illinois) | 687.94 mi (1,107.14 km) |
| Difficult Run to Alton (Texas) | 1,493.39 mi (2,403.38 km) |
| Difficult Run to Altoona (Iowa) | 869.87 mi (1,399.92 km) |
| Difficult Run to Altoona (Pennsylvania) | 124.33 mi (200.09 km) |
