| Difficult Run to Alderwood Manor (Washington) | 2,303.94 mi (3,707.83 km) |
| Difficult Run to Aldine (Texas) | 1,197.61 mi (1,927.36 km) |
| Difficult Run to Alexander City (Alabama) | 633.21 mi (1,019.05 km) |
| Difficult Run to Alexandria (Louisiana) | 1,001.61 mi (1,611.94 km) |
| Difficult Run to Alexandria (Minnesota) | 1,035.37 mi (1,666.27 km) |
| Difficult Run to Alexandria (Virginia) | 15.17 mi (24.41 km) |
| Difficult Run to Algonquin (Illinois) | 617.94 mi (994.48 km) |
| Difficult Run to Alhambra (California) | 2,270.94 mi (3,654.72 km) |
| Difficult Run to Alice (Texas) | 1,417.21 mi (2,280.78 km) |
| Difficult Run to Aliso Viejo (California) | 2,261.53 mi (3,639.58 km) |
| Difficult Run to Allen (Texas) | 1,149.20 mi (1,849.47 km) |
| Difficult Run to Allen Park (Michigan) | 385.21 mi (619.93 km) |
| Difficult Run to Allendale (Michigan) | 529.84 mi (852.69 km) |
| Difficult Run to Allentown (Pennsylvania) | 153.59 mi (247.17 km) |
| Difficult Run to Alliance (Ohio) | 243.34 mi (391.62 km) |
