| Difficult Run to Alachua (Florida) | 694.83 mi (1,118.23 km) |
| Difficult Run to Alafaya (Florida) | 749.74 mi (1,206.59 km) |
| Difficult Run to Alameda (California) | 2,410.85 mi (3,879.89 km) |
| Difficult Run to Alamo (California) | 2,395.88 mi (3,855.79 km) |
| Difficult Run to Alamo (Texas) | 1,489.30 mi (2,396.80 km) |
| Difficult Run to Alamogordo (New Mexico) | 1,647.33 mi (2,651.12 km) |
| Difficult Run to Albany (California) | 2,410.33 mi (3,879.05 km) |
| Difficult Run to Albany (Georgia) | 635.63 mi (1,022.95 km) |
| Difficult Run to Albany (New York) | 319.50 mi (514.19 km) |
| Difficult Run to Albany (Oregon) | 2,359.09 mi (3,796.59 km) |
| Difficult Run to Albemarle (North Carolina) | 290.56 mi (467.61 km) |
| Difficult Run to Albert Lea (Minnesota) | 892.34 mi (1,436.09 km) |
| Difficult Run to Albertville (Alabama) | 586.54 mi (943.94 km) |
| Difficult Run to Albuquerque (New Mexico) | 1,630.63 mi (2,624.24 km) |
| Difficult Run to Alcoa (Tennessee) | 421.99 mi (679.13 km) |
