| Difficult Run to Snodland | 3,704.94 mi (5,962.53 km) |
| Difficult Run to Soham | 3,678.13 mi (5,919.38 km) |
| Difficult Run to Solihull | 3,591.50 mi (5,779.95 km) |
| Difficult Run to Sompting | 3,683.92 mi (5,928.70 km) |
| Difficult Run to South Hayling | 3,658.52 mi (5,887.83 km) |
| Difficult Run to South Normanton | 3,595.04 mi (5,785.66 km) |
| Difficult Run to South Ockendon | 3,694.45 mi (5,945.64 km) |
| Difficult Run to South Shields | 3,555.79 mi (5,722.50 km) |
| Difficult Run to Southall | 3,667.21 mi (5,901.80 km) |
| Difficult Run to Southampton | 3,638.33 mi (5,855.33 km) |
| Difficult Run to Southborough | 3,701.34 mi (5,956.73 km) |
| Difficult Run to Southbourne | 3,625.90 mi (5,835.32 km) |
| Difficult Run to Southend | 3,710.63 mi (5,971.68 km) |
| Difficult Run to Southgate | 3,674.82 mi (5,914.06 km) |
| Difficult Run to Southport | 3,518.91 mi (5,663.13 km) |
