| Difficult Run to Rivalta di Torino | 4,175.09 mi (6,719.16 km) |
| Difficult Run to Rivarolo Canavese | 4,174.41 mi (6,718.06 km) |
| Difficult Run to Rivoli | 4,173.94 mi (6,717.31 km) |
| Difficult Run to Rocca di Papa | 4,512.72 mi (7,262.52 km) |
| Difficult Run to Rocca Priora | 4,514.34 mi (7,265.12 km) |
| Difficult Run to Roccapiemonte | 4,636.55 mi (7,461.81 km) |
| Difficult Run to Roccastrada | 4,401.09 mi (7,082.87 km) |
| Difficult Run to Romano di Lombardia | 4,256.01 mi (6,849.39 km) |
| Difficult Run to Rome | 4,497.90 mi (7,238.67 km) |
| Difficult Run to Roncade | 4,363.97 mi (7,023.14 km) |
| Difficult Run to Ronchi dei Legionari | 4,404.00 mi (7,087.55 km) |
| Difficult Run to Ronciglione | 4,472.08 mi (7,197.13 km) |
| Difficult Run to Rosa | 4,335.15 mi (6,976.75 km) |
| Difficult Run to Rosarno | 4,779.80 mi (7,692.35 km) |
| Difficult Run to Rosignano Marittimo | 4,357.05 mi (7,012.00 km) |
