| Difficult Run to Saint-Raphael | 4,192.85 mi (6,747.74 km) |
| Difficult Run to Saint-Remy-de-Provence | 4,095.03 mi (6,590.31 km) |
| Difficult Run to Saint-Saulve | 3,855.09 mi (6,204.17 km) |
| Difficult Run to Saint-Sebastien-sur-Loire | 3,719.64 mi (5,986.19 km) |
| Difficult Run to Saint-Sulpice-la-Pointe | 3,953.82 mi (6,363.06 km) |
| Difficult Run to Saint-Vallier | 3,990.42 mi (6,421.96 km) |
| Difficult Run to Sainte-Foy-les-Lyon | 4,035.47 mi (6,494.46 km) |
| Difficult Run to Sainte-Genevieve-des-Bois | 3,849.15 mi (6,194.60 km) |
| Difficult Run to Sainte-Luce-sur-Loire | 3,719.28 mi (5,985.60 km) |
| Difficult Run to Sainte-Maxime | 4,190.72 mi (6,744.32 km) |
| Difficult Run to Sainte-Savine | 3,930.49 mi (6,325.51 km) |
| Difficult Run to Saintes | 3,795.15 mi (6,107.71 km) |
| Difficult Run to Sallanches | 4,108.84 mi (6,612.53 km) |
| Difficult Run to Sallaumines | 3,825.44 mi (6,156.45 km) |
| Difficult Run to Salon-de-Provence | 4,111.47 mi (6,616.78 km) |
