| Destrehan to Yonkers (New York) | 1,195.69 mi (1,924.29 km) |
| Destrehan to Yorba Linda (California) | 1,624.78 mi (2,614.83 km) |
| Destrehan to York (Pennsylvania) | 1,033.98 mi (1,664.03 km) |
| Destrehan to Yorktown (Indiana) | 757.32 mi (1,218.79 km) |
| Destrehan to Yorkville (Illinois) | 815.00 mi (1,311.62 km) |
| Destrehan to Youngstown (Ohio) | 942.47 mi (1,516.75 km) |
| Destrehan to Youngsville (Louisiana) | 97.89 mi (157.54 km) |
| Destrehan to Ypsilanti (Michigan) | 927.60 mi (1,492.83 km) |
| Destrehan to Yuba City (California) | 1,877.85 mi (3,022.11 km) |
| Destrehan to Yucaipa (California) | 1,583.50 mi (2,548.39 km) |
| Destrehan to Yucca Valley (California) | 1,548.34 mi (2,491.81 km) |
| Destrehan to Yukon (Oklahoma) | 576.03 mi (927.03 km) |
| Destrehan to Yulee (Florida) | 526.87 mi (847.92 km) |
| Destrehan to Yuma (Arizona) | 1,436.34 mi (2,311.57 km) |
| Destrehan to Zachary (Louisiana) | 67.85 mi (109.19 km) |
