| Destrehan to Seymour (Tennessee) | 559.72 mi (900.78 km) |
| Destrehan to Shady Hills (Florida) | 483.79 mi (778.59 km) |
| Destrehan to Shafter (California) | 1,712.32 mi (2,755.72 km) |
| Destrehan to Shaker Heights (Ohio) | 935.45 mi (1,505.46 km) |
| Destrehan to Shakopee (Minnesota) | 1,037.33 mi (1,669.43 km) |
| Destrehan to Sharon (Pennsylvania) | 954.49 mi (1,536.11 km) |
| Destrehan to Sharonville (Ohio) | 727.23 mi (1,170.37 km) |
| Destrehan to Shasta Lake (California) | 1,937.00 mi (3,117.30 km) |
| Destrehan to Shawnee (Kansas) | 674.44 mi (1,085.41 km) |
| Destrehan to Shawnee (Oklahoma) | 534.50 mi (860.20 km) |
| Destrehan to Sheboygan (Wisconsin) | 962.89 mi (1,549.63 km) |
| Destrehan to Shelby (North Carolina) | 631.27 mi (1,015.93 km) |
| Destrehan to Shelbyville (Indiana) | 710.57 mi (1,143.55 km) |
| Destrehan to Shelbyville (Kentucky) | 640.74 mi (1,031.17 km) |
| Destrehan to Shelbyville (Tennessee) | 444.99 mi (716.15 km) |
