| Destrehan to Scottsboro (Alabama) | 410.04 mi (659.89 km) |
| Destrehan to Scottsdale (Arizona) | 1,285.50 mi (2,068.81 km) |
| Destrehan to Scranton (Pennsylvania) | 1,139.63 mi (1,834.06 km) |
| Destrehan to Seabrook (Maryland) | 988.54 mi (1,590.89 km) |
| Destrehan to Seabrook (Texas) | 280.50 mi (451.42 km) |
| Destrehan to Seaford (New York) | 1,201.45 mi (1,933.54 km) |
| Destrehan to Seagoville (Texas) | 409.24 mi (658.61 km) |
| Destrehan to Seal Beach (California) | 1,641.70 mi (2,642.06 km) |
| Destrehan to Searcy (Arkansas) | 373.33 mi (600.81 km) |
| Destrehan to Seaside (California) | 1,864.77 mi (3,001.06 km) |
| Destrehan to SeaTac (Washington) | 2,079.68 mi (3,346.93 km) |
| Destrehan to Seattle (Washington) | 2,085.77 mi (3,356.72 km) |
| Destrehan to Sebastian (Florida) | 616.58 mi (992.29 km) |
| Destrehan to Sebring (Florida) | 566.61 mi (911.88 km) |
| Destrehan to Secaucus (New Jersey) | 1,180.68 mi (1,900.13 km) |
