| Destrehan to Santa Rosa (California) | 1,927.26 mi (3,101.62 km) |
| Destrehan to Santaquin (Utah) | 1,391.06 mi (2,238.70 km) |
| Destrehan to Santee (California) | 1,578.07 mi (2,539.66 km) |
| Destrehan to Sapulpa (Oklahoma) | 533.54 mi (858.64 km) |
| Destrehan to Saraland (Alabama) | 148.30 mi (238.67 km) |
| Destrehan to Sarasota (Florida) | 507.73 mi (817.11 km) |
| Destrehan to Sarasota Springs (Florida) | 512.41 mi (824.65 km) |
| Destrehan to Saratoga (California) | 1,880.48 mi (3,026.34 km) |
| Destrehan to Saratoga Springs (New York) | 1,287.10 mi (2,071.39 km) |
| Destrehan to Saratoga Springs (Utah) | 1,407.26 mi (2,264.76 km) |
| Destrehan to Sartell (Minnesota) | 1,101.65 mi (1,772.94 km) |
| Destrehan to Satellite Beach (Florida) | 602.28 mi (969.28 km) |
| Destrehan to Sauk Rapids (Minnesota) | 1,099.57 mi (1,769.59 km) |
| Destrehan to Sault Ste. Marie (Michigan) | 1,185.94 mi (1,908.59 km) |
| Destrehan to Savage (Minnesota) | 1,034.98 mi (1,665.63 km) |
