| Destrehan to Sanford (Maine) | 1,423.67 mi (2,291.17 km) |
| Destrehan to Sanford (North Carolina) | 753.46 mi (1,212.58 km) |
| Destrehan to Sanger (California) | 1,740.62 mi (2,801.26 km) |
| Destrehan to Santa Ana (California) | 1,630.78 mi (2,624.49 km) |
| Destrehan to Santa Barbara (California) | 1,737.46 mi (2,796.17 km) |
| Destrehan to Santa Clara (California) | 1,878.02 mi (3,022.39 km) |
| Destrehan to Santa Clara (Oregon) | 2,035.67 mi (3,276.10 km) |
| Destrehan to Santa Clarita (California) | 1,667.74 mi (2,683.97 km) |
| Destrehan to Santa Cruz (California) | 1,878.89 mi (3,023.78 km) |
| Destrehan to Santa Fe (New Mexico) | 987.00 mi (1,588.42 km) |
| Destrehan to Santa Fe (Texas) | 286.84 mi (461.62 km) |
| Destrehan to Santa Fe Springs (California) | 1,641.57 mi (2,641.85 km) |
| Destrehan to Santa Maria (California) | 1,779.91 mi (2,864.49 km) |
| Destrehan to Santa Monica (California) | 1,665.74 mi (2,680.76 km) |
| Destrehan to Santa Paula (California) | 1,699.97 mi (2,735.84 km) |
