| Destrehan to Orangevale (California) | 1,850.46 mi (2,978.03 km) |
| Destrehan to Orchards (Washington) | 2,043.58 mi (3,288.82 km) |
| Destrehan to Orcutt (California) | 1,778.53 mi (2,862.27 km) |
| Destrehan to Oregon (Ohio) | 895.53 mi (1,441.22 km) |
| Destrehan to Oregon (Wisconsin) | 897.27 mi (1,444.01 km) |
| Destrehan to Oregon City (Oregon) | 2,037.96 mi (3,279.77 km) |
| Destrehan to Orem (Utah) | 1,395.54 mi (2,245.91 km) |
| Destrehan to Orinda (California) | 1,893.72 mi (3,047.64 km) |
| Destrehan to Orland Park (Illinois) | 816.64 mi (1,314.26 km) |
| Destrehan to Orlando (Florida) | 553.98 mi (891.55 km) |
| Destrehan to Ormond Beach (Florida) | 558.24 mi (898.41 km) |
| Destrehan to Oro Valley (Arizona) | 1,227.93 mi (1,976.17 km) |
| Destrehan to Oroville (California) | 1,878.49 mi (3,023.13 km) |
| Destrehan to Oshkosh (Wisconsin) | 976.49 mi (1,571.50 km) |
| Destrehan to Oskaloosa (Iowa) | 793.05 mi (1,276.29 km) |
