| Destrehan to Emeryville (California) | 1,899.53 mi (3,057.00 km) |
| Destrehan to Emmaus (Pennsylvania) | 1,109.63 mi (1,785.77 km) |
| Destrehan to Emporia (Kansas) | 671.15 mi (1,080.11 km) |
| Destrehan to Encinitas (California) | 1,594.12 mi (2,565.49 km) |
| Destrehan to Endicott (New York) | 1,155.19 mi (1,859.10 km) |
| Destrehan to Endwell (New York) | 1,157.74 mi (1,863.20 km) |
| Destrehan to Englewood (Colorado) | 1,063.51 mi (1,711.55 km) |
| Destrehan to Englewood (Florida) | 528.70 mi (850.86 km) |
| Destrehan to Englewood (New Jersey) | 1,188.97 mi (1,913.47 km) |
| Destrehan to Englewood (Ohio) | 764.98 mi (1,231.12 km) |
| Destrehan to Enid (Oklahoma) | 621.20 mi (999.72 km) |
| Destrehan to Ennis (Texas) | 404.87 mi (651.58 km) |
| Destrehan to Ensley (Florida) | 188.74 mi (303.75 km) |
| Destrehan to Enterprise (Alabama) | 284.80 mi (458.34 km) |
| Destrehan to Enterprise (Nevada) | 1,495.42 mi (2,406.65 km) |
