| Des Moines to Wichita (Kansas) | 333.77 mi (537.16 km) |
| Des Moines to Wichita Falls (Texas) | 593.64 mi (955.37 km) |
| Des Moines to Wickliffe (Ohio) | 626.91 mi (1,008.91 km) |
| Des Moines to Wildomar (California) | 1,400.61 mi (2,254.06 km) |
| Des Moines to Wildwood (Florida) | 1,098.32 mi (1,767.57 km) |
| Des Moines to Wildwood (Missouri) | 258.66 mi (416.27 km) |
| Des Moines to Wilkes-Barre (Pennsylvania) | 917.66 mi (1,476.83 km) |
| Des Moines to Wilkinsburg (Pennsylvania) | 719.70 mi (1,158.24 km) |
| Des Moines to Williamsburg (Virginia) | 948.05 mi (1,525.73 km) |
| Des Moines to Williamsport (Pennsylvania) | 857.87 mi (1,380.61 km) |
| Des Moines to Williamstown (New Jersey) | 983.69 mi (1,583.09 km) |
| Des Moines to Willimantic (Connecticut) | 1,102.07 mi (1,773.60 km) |
| Des Moines to Williston (North Dakota) | 669.41 mi (1,077.31 km) |
| Des Moines to Willmar (Minnesota) | 255.75 mi (411.59 km) |
| Des Moines to Willoughby (Ohio) | 629.86 mi (1,013.66 km) |
