| Des Moines to Wayne (Michigan) | 527.45 mi (848.85 km) |
| Des Moines to Waynesboro (Pennsylvania) | 848.16 mi (1,364.98 km) |
| Des Moines to Waynesboro (Virginia) | 816.08 mi (1,313.36 km) |
| Des Moines to Weatherford (Oklahoma) | 498.80 mi (802.75 km) |
| Des Moines to Weatherford (Texas) | 650.77 mi (1,047.31 km) |
| Des Moines to Webb City (Missouri) | 309.57 mi (498.21 km) |
| Des Moines to Webster (Texas) | 836.21 mi (1,345.75 km) |
| Des Moines to Webster Groves (Missouri) | 268.64 mi (432.34 km) |
| Des Moines to Weddington (North Carolina) | 830.46 mi (1,336.50 km) |
| Des Moines to Weigelstown (Pennsylvania) | 883.32 mi (1,421.57 km) |
| Des Moines to Weirton (West Virginia) | 684.35 mi (1,101.36 km) |
| Des Moines to Wekiwa Springs (Florida) | 1,122.38 mi (1,806.29 km) |
| Des Moines to Welby (Colorado) | 606.19 mi (975.56 km) |
| Des Moines to Wellington (Colorado) | 595.58 mi (958.49 km) |
| Des Moines to Wellington (Florida) | 1,279.59 mi (2,059.31 km) |
