| Des Moines to Vinings (Georgia) | 729.60 mi (1,174.17 km) |
| Des Moines to Virginia Beach (Virginia) | 996.66 mi (1,603.98 km) |
| Des Moines to Visalia (California) | 1,422.69 mi (2,289.60 km) |
| Des Moines to Vista (California) | 1,414.63 mi (2,276.62 km) |
| Des Moines to Wabash (Indiana) | 407.88 mi (656.43 km) |
| Des Moines to Waco (Texas) | 719.54 mi (1,157.99 km) |
| Des Moines to Waconia (Minnesota) | 226.09 mi (363.86 km) |
| Des Moines to Wade Hampton (South Carolina) | 765.93 mi (1,232.64 km) |
| Des Moines to Wadsworth (Ohio) | 617.22 mi (993.32 km) |
| Des Moines to Waggaman (Louisiana) | 825.70 mi (1,328.83 km) |
| Des Moines to Wahiawa (Hawaii) | 3,941.87 mi (6,343.82 km) |
| Des Moines to Waianae (Hawaii) | 3,951.86 mi (6,359.90 km) |
| Des Moines to Waihee-Waiehu (Hawaii) | 3,887.75 mi (6,256.74 km) |
| Des Moines to Wailuku (Hawaii) | 3,889.20 mi (6,259.06 km) |
| Des Moines to Waimalu (Hawaii) | 3,942.08 mi (6,344.17 km) |
