| Des Moines to The Villages (Florida) | 1,091.56 mi (1,756.69 km) |
| Des Moines to The Woodlands (Texas) | 794.69 mi (1,278.92 km) |
| Des Moines to Thibodaux (Louisiana) | 828.61 mi (1,333.52 km) |
| Des Moines to Thomasville (Georgia) | 914.27 mi (1,471.38 km) |
| Des Moines to Thomasville (North Carolina) | 827.18 mi (1,331.22 km) |
| Des Moines to Thonotosassa (Florida) | 1,131.64 mi (1,821.20 km) |
| Des Moines to Thornton (Colorado) | 603.67 mi (971.51 km) |
| Des Moines to Thousand Oaks (California) | 1,462.64 mi (2,353.89 km) |
| Des Moines to Three Lakes (Florida) | 1,334.17 mi (2,147.14 km) |
| Des Moines to Tiffin (Ohio) | 541.61 mi (871.64 km) |
| Des Moines to Tifton (Georgia) | 894.12 mi (1,438.94 km) |
| Des Moines to Tigard (Oregon) | 1,477.76 mi (2,378.22 km) |
| Des Moines to Tillmans Corner (Alabama) | 816.55 mi (1,314.12 km) |
| Des Moines to Timberlake (Virginia) | 819.55 mi (1,318.94 km) |
| Des Moines to Timberlane (Louisiana) | 832.37 mi (1,339.57 km) |
