| Des Moines to Pottsville (Pennsylvania) | 906.22 mi (1,458.42 km) |
| Des Moines to Poughkeepsie (New York) | 1,014.59 mi (1,632.82 km) |
| Des Moines to Poulsbo (Washington) | 1,479.17 mi (2,380.50 km) |
| Des Moines to Poway (California) | 1,411.09 mi (2,270.93 km) |
| Des Moines to Powder Springs (Georgia) | 721.36 mi (1,160.92 km) |
| Des Moines to Powell (Ohio) | 558.15 mi (898.26 km) |
| Des Moines to Powell (Tennessee) | 641.57 mi (1,032.51 km) |
| Des Moines to Prairie Ridge (Washington) | 1,452.01 mi (2,336.79 km) |
| Des Moines to Prairie Village (Kansas) | 186.61 mi (300.32 km) |
| Des Moines to Prairieville (Louisiana) | 791.73 mi (1,274.17 km) |
| Des Moines to Prattville (Alabama) | 742.44 mi (1,194.83 km) |
| Des Moines to Preakness (New Jersey) | 1,005.82 mi (1,618.71 km) |
| Des Moines to Prescott (Arizona) | 1,129.32 mi (1,817.46 km) |
| Des Moines to Prescott Valley (Arizona) | 1,122.57 mi (1,806.60 km) |
| Des Moines to Prichard (Alabama) | 805.86 mi (1,296.91 km) |
