| Des Moines to Pell City (Alabama) | 683.63 mi (1,100.19 km) |
| Des Moines to Pella (Iowa) | 37.61 mi (60.54 km) |
| Des Moines to Pembroke Pines (Florida) | 1,314.29 mi (2,115.15 km) |
| Des Moines to Pendleton (Oregon) | 1,286.60 mi (2,070.58 km) |
| Des Moines to Pensacola (Florida) | 848.02 mi (1,364.76 km) |
| Des Moines to Peoria (Arizona) | 1,151.52 mi (1,853.19 km) |
| Des Moines to Peoria (Illinois) | 215.38 mi (346.63 km) |
| Des Moines to Perris (California) | 1,392.94 mi (2,241.73 km) |
| Des Moines to Perry (Georgia) | 831.02 mi (1,337.39 km) |
| Des Moines to Perry Hall (Maryland) | 911.04 mi (1,466.18 km) |
| Des Moines to Perrysburg (Ohio) | 515.16 mi (829.08 km) |
| Des Moines to Perth Amboy (New Jersey) | 1,008.19 mi (1,622.52 km) |
| Des Moines to Peru (Indiana) | 395.79 mi (636.97 km) |
| Des Moines to Petal (Mississippi) | 746.84 mi (1,201.92 km) |
| Des Moines to Petaluma (California) | 1,547.53 mi (2,490.51 km) |
