| Des Moines to New Lenox (Illinois) | 291.66 mi (469.39 km) |
| Des Moines to New London (Connecticut) | 1,110.89 mi (1,787.80 km) |
| Des Moines to New Milford (New Jersey) | 1,016.42 mi (1,635.76 km) |
| Des Moines to New Orleans (Louisiana) | 820.94 mi (1,321.17 km) |
| Des Moines to New Philadelphia (Ohio) | 638.23 mi (1,027.14 km) |
| Des Moines to New Port Richey (Florida) | 1,106.38 mi (1,780.54 km) |
| Des Moines to New Port Richey East (Florida) | 1,106.31 mi (1,780.44 km) |
| Des Moines to New Providence (New Jersey) | 999.24 mi (1,608.12 km) |
| Des Moines to New River (Arizona) | 1,137.53 mi (1,830.68 km) |
| Des Moines to New Rochelle (New York) | 1,028.62 mi (1,655.40 km) |
| Des Moines to New Smyrna Beach (Florida) | 1,119.95 mi (1,802.39 km) |
| Des Moines to New Ulm (Minnesota) | 194.19 mi (312.52 km) |
| Des Moines to New York (New York) | 1,024.01 mi (1,647.98 km) |
| Des Moines to Newark (California) | 1,532.64 mi (2,466.54 km) |
| Des Moines to Newark (Delaware) | 943.60 mi (1,518.57 km) |
