| Des Moines to Monticello (Minnesota) | 257.66 mi (414.66 km) |
| Des Moines to Montrose (Colorado) | 782.77 mi (1,259.75 km) |
| Des Moines to Moody (Alabama) | 674.17 mi (1,084.98 km) |
| Des Moines to Moore (Oklahoma) | 479.25 mi (771.28 km) |
| Des Moines to Moorestown-Lenola (New Jersey) | 980.07 mi (1,577.27 km) |
| Des Moines to Mooresville (North Carolina) | 803.70 mi (1,293.43 km) |
| Des Moines to Moorhead (Minnesota) | 397.33 mi (639.45 km) |
| Des Moines to Moorpark (California) | 1,459.65 mi (2,349.08 km) |
| Des Moines to Moraga (California) | 1,530.08 mi (2,462.42 km) |
| Des Moines to Moreno Valley (California) | 1,387.43 mi (2,232.86 km) |
| Des Moines to Morgan City (Louisiana) | 831.09 mi (1,337.52 km) |
| Des Moines to Morgan Hill (California) | 1,521.66 mi (2,448.87 km) |
| Des Moines to Morganton (North Carolina) | 757.43 mi (1,218.96 km) |
| Des Moines to Morgantown (West Virginia) | 728.30 mi (1,172.09 km) |
| Des Moines to Morris (Illinois) | 268.47 mi (432.07 km) |
