| Des Moines to Mitchell (South Dakota) | 269.63 mi (433.93 km) |
| Des Moines to Mitchellville (Maryland) | 902.66 mi (1,452.70 km) |
| Des Moines to Moberly (Missouri) | 161.14 mi (259.33 km) |
| Des Moines to Mobile (Alabama) | 812.31 mi (1,307.29 km) |
| Des Moines to Modesto (California) | 1,476.84 mi (2,376.74 km) |
| Des Moines to Mokena (Illinois) | 296.36 mi (476.94 km) |
| Des Moines to Moline (Illinois) | 161.42 mi (259.78 km) |
| Des Moines to Moncks Corner (South Carolina) | 943.78 mi (1,518.86 km) |
| Des Moines to Monfort Heights (Ohio) | 501.53 mi (807.13 km) |
| Des Moines to Monmouth (Oregon) | 1,500.05 mi (2,414.09 km) |
| Des Moines to Monroe (Georgia) | 761.34 mi (1,225.26 km) |
| Des Moines to Monroe (Louisiana) | 631.23 mi (1,015.86 km) |
| Des Moines to Monroe (Michigan) | 527.37 mi (848.73 km) |
| Des Moines to Monroe (North Carolina) | 839.25 mi (1,350.64 km) |
| Des Moines to Monroe (Ohio) | 507.03 mi (815.99 km) |
