| Des Moines to Mendota Heights (Minnesota) | 229.85 mi (369.91 km) |
| Des Moines to Menifee (California) | 1,394.42 mi (2,244.10 km) |
| Des Moines to Menlo Park (California) | 1,540.88 mi (2,479.81 km) |
| Des Moines to Menomonee Falls (Wisconsin) | 300.52 mi (483.65 km) |
| Des Moines to Menomonie (Wisconsin) | 244.65 mi (393.72 km) |
| Des Moines to Mentor (Ohio) | 633.40 mi (1,019.36 km) |
| Des Moines to Mequon (Wisconsin) | 309.12 mi (497.48 km) |
| Des Moines to Merced (California) | 1,457.42 mi (2,345.49 km) |
| Des Moines to Mercedes (Texas) | 1,093.18 mi (1,759.31 km) |
| Des Moines to Mercer Island (Washington) | 1,459.00 mi (2,348.03 km) |
| Des Moines to Mercerville (New Jersey) | 990.27 mi (1,593.68 km) |
| Des Moines to Meriden (Connecticut) | 1,073.65 mi (1,727.87 km) |
| Des Moines to Meridian (Idaho) | 1,163.91 mi (1,873.13 km) |
| Des Moines to Meridian (Mississippi) | 690.17 mi (1,110.72 km) |
| Des Moines to Merriam (Kansas) | 185.45 mi (298.45 km) |
