| Des Moines to Livermore (California) | 1,514.89 mi (2,437.97 km) |
| Des Moines to Livingston (California) | 1,468.24 mi (2,362.91 km) |
| Des Moines to Livonia (Michigan) | 528.52 mi (850.57 km) |
| Des Moines to Lochearn (Maryland) | 899.11 mi (1,446.97 km) |
| Des Moines to Lockhart (Florida) | 1,126.10 mi (1,812.29 km) |
| Des Moines to Lockhart (Texas) | 839.37 mi (1,350.83 km) |
| Des Moines to Lockport (Illinois) | 288.40 mi (464.14 km) |
| Des Moines to Lockport (New York) | 768.25 mi (1,236.37 km) |
| Des Moines to Lodi (California) | 1,481.17 mi (2,383.71 km) |
| Des Moines to Lodi (New Jersey) | 1,013.83 mi (1,631.60 km) |
| Des Moines to Logan (Utah) | 939.48 mi (1,511.94 km) |
| Des Moines to Logansport (Indiana) | 381.74 mi (614.35 km) |
| Des Moines to Loganville (Georgia) | 752.57 mi (1,211.14 km) |
| Des Moines to Loma Linda (California) | 1,385.64 mi (2,229.97 km) |
| Des Moines to Lombard (Illinois) | 289.22 mi (465.45 km) |
