| Des Moines to Land O' Lakes (Florida) | 1,117.17 mi (1,797.91 km) |
| Des Moines to Landover (Maryland) | 899.15 mi (1,447.05 km) |
| Des Moines to Langley Park (Maryland) | 893.04 mi (1,437.20 km) |
| Des Moines to Lanham (Maryland) | 900.72 mi (1,449.57 km) |
| Des Moines to Lansdale (Pennsylvania) | 959.72 mi (1,544.52 km) |
| Des Moines to Lansdowne (Pennsylvania) | 964.33 mi (1,551.95 km) |
| Des Moines to Lansdowne (Virginia) | 865.30 mi (1,392.56 km) |
| Des Moines to Lansing (Illinois) | 313.42 mi (504.40 km) |
| Des Moines to Lansing (Kansas) | 174.62 mi (281.02 km) |
| Des Moines to Lansing (Michigan) | 470.08 mi (756.52 km) |
| Des Moines to Lantana (Florida) | 1,290.42 mi (2,076.73 km) |
| Des Moines to Lantana (Texas) | 616.68 mi (992.45 km) |
| Des Moines to Laplace (Louisiana) | 813.54 mi (1,309.27 km) |
| Des Moines to Laramie (Wyoming) | 621.20 mi (999.72 km) |
| Des Moines to Laredo (Texas) | 1,023.44 mi (1,647.07 km) |
