| Des Moines to Firestone (Colorado) | 600.05 mi (965.69 km) |
| Des Moines to Fish Hawk (Florida) | 1,145.54 mi (1,843.57 km) |
| Des Moines to Fishers (Indiana) | 415.13 mi (668.08 km) |
| Des Moines to Fitchburg (Massachusetts) | 1,116.77 mi (1,797.27 km) |
| Des Moines to Fitchburg (Wisconsin) | 235.14 mi (378.42 km) |
| Des Moines to Five Corners (Washington) | 1,467.68 mi (2,362.00 km) |
| Des Moines to Five Forks (South Carolina) | 773.89 mi (1,245.46 km) |
| Des Moines to Flagstaff (Arizona) | 1,067.80 mi (1,718.46 km) |
| Des Moines to Flat Rock (Michigan) | 533.15 mi (858.02 km) |
| Des Moines to Fleming Island (Florida) | 1,033.57 mi (1,663.37 km) |
| Des Moines to Flint (Michigan) | 516.37 mi (831.02 km) |
| Des Moines to Floral Park (New York) | 1,035.13 mi (1,665.88 km) |
| Des Moines to Florence (Alabama) | 566.41 mi (911.55 km) |
| Des Moines to Florence (Arizona) | 1,138.49 mi (1,832.21 km) |
| Des Moines to Florence (Kentucky) | 504.73 mi (812.28 km) |
