| Des Moines to Felida (Washington) | 1,474.29 mi (2,372.63 km) |
| Des Moines to Fenton (Michigan) | 513.37 mi (826.19 km) |
| Des Moines to Fergus Falls (Minnesota) | 347.92 mi (559.93 km) |
| Des Moines to Ferguson (Missouri) | 262.08 mi (421.77 km) |
| Des Moines to Fernandina Beach (Florida) | 1,012.51 mi (1,629.48 km) |
| Des Moines to Ferndale (Maryland) | 907.09 mi (1,459.82 km) |
| Des Moines to Ferndale (Michigan) | 541.06 mi (870.75 km) |
| Des Moines to Ferndale (Washington) | 1,486.70 mi (2,392.62 km) |
| Des Moines to Fernley (Nevada) | 1,344.80 mi (2,164.24 km) |
| Des Moines to Ferry Pass (Florida) | 843.02 mi (1,356.71 km) |
| Des Moines to Festus (Missouri) | 287.11 mi (462.06 km) |
| Des Moines to Fife (Washington) | 1,462.41 mi (2,353.52 km) |
| Des Moines to Fillmore (California) | 1,458.11 mi (2,346.60 km) |
| Des Moines to Findlay (Ohio) | 518.56 mi (834.54 km) |
| Des Moines to Finneytown (Ohio) | 505.29 mi (813.18 km) |
