| Des Moines to Eagle (Idaho) | 1,163.25 mi (1,872.07 km) |
| Des Moines to Eagle Mountain (Utah) | 962.44 mi (1,548.90 km) |
| Des Moines to Eagle Pass (Texas) | 968.85 mi (1,559.22 km) |
| Des Moines to Easley (South Carolina) | 758.10 mi (1,220.05 km) |
| Des Moines to East Bakersfield (California) | 1,430.98 mi (2,302.95 km) |
| Des Moines to East Bethel (Minnesota) | 262.19 mi (421.95 km) |
| Des Moines to East Chicago (Indiana) | 317.99 mi (511.76 km) |
| Des Moines to East Cleveland (Ohio) | 621.58 mi (1,000.34 km) |
| Des Moines to East Glenville (New York) | 1,008.90 mi (1,623.67 km) |
| Des Moines to East Grand Rapids (Michigan) | 419.87 mi (675.71 km) |
| Des Moines to East Hemet (California) | 1,380.91 mi (2,222.36 km) |
| Des Moines to East Highland Park (Virginia) | 905.44 mi (1,457.16 km) |
| Des Moines to East Honolulu (Hawaii) | 3,934.91 mi (6,332.63 km) |
| Des Moines to East Islip (New York) | 1,061.71 mi (1,708.66 km) |
| Des Moines to East Lake (Florida) | 1,114.81 mi (1,794.12 km) |
