| Des Moines to Dover (New Jersey) | 989.08 mi (1,591.76 km) |
| Des Moines to Dover (Ohio) | 635.58 mi (1,022.86 km) |
| Des Moines to Downers Grove (Illinois) | 288.98 mi (465.06 km) |
| Des Moines to Downey (California) | 1,433.42 mi (2,306.87 km) |
| Des Moines to Dranesville (Virginia) | 872.96 mi (1,404.89 km) |
| Des Moines to Draper (Utah) | 952.28 mi (1,532.55 km) |
| Des Moines to Drexel Heights (Arizona) | 1,159.87 mi (1,866.63 km) |
| Des Moines to Drexel Hill (Pennsylvania) | 962.77 mi (1,549.42 km) |
| Des Moines to Duarte (California) | 1,416.97 mi (2,280.39 km) |
| Des Moines to Dublin (California) | 1,521.24 mi (2,448.19 km) |
| Des Moines to Dublin (Georgia) | 857.02 mi (1,379.24 km) |
| Des Moines to Dublin (Ohio) | 555.89 mi (894.61 km) |
| Des Moines to Dubuque (Iowa) | 162.19 mi (261.02 km) |
| Des Moines to Duluth (Georgia) | 734.12 mi (1,181.46 km) |
| Des Moines to Duluth (Minnesota) | 366.80 mi (590.30 km) |
