| Des Moines to Dixon (Illinois) | 213.89 mi (344.22 km) |
| Des Moines to Dobbs Ferry (New York) | 1,023.31 mi (1,646.85 km) |
| Des Moines to Doctor Phillips (Florida) | 1,134.49 mi (1,825.79 km) |
| Des Moines to Dodge City (Kansas) | 430.48 mi (692.79 km) |
| Des Moines to Dolton (Illinois) | 310.62 mi (499.89 km) |
| Des Moines to Donna (Texas) | 1,095.48 mi (1,763.00 km) |
| Des Moines to Dorado (Puerto Rico) | 2,266.58 mi (3,647.71 km) |
| Des Moines to Doral (Florida) | 1,325.32 mi (2,132.90 km) |
| Des Moines to Doraville (Georgia) | 734.57 mi (1,182.17 km) |
| Des Moines to Dothan (Alabama) | 846.64 mi (1,362.54 km) |
| Des Moines to Douglas (Arizona) | 1,128.71 mi (1,816.48 km) |
| Des Moines to Douglas (Georgia) | 915.12 mi (1,472.74 km) |
| Des Moines to Douglasville (Georgia) | 727.37 mi (1,170.58 km) |
| Des Moines to Dover (Delaware) | 964.93 mi (1,552.91 km) |
| Des Moines to Dover (New Hampshire) | 1,161.66 mi (1,869.50 km) |
