| Des Moines to Decatur (Alabama) | 602.51 mi (969.65 km) |
| Des Moines to Decatur (Georgia) | 740.73 mi (1,192.10 km) |
| Des Moines to Decatur (Illinois) | 272.06 mi (437.85 km) |
| Des Moines to Deer Park (New York) | 1,054.32 mi (1,696.77 km) |
| Des Moines to Deer Park (Texas) | 825.31 mi (1,328.21 km) |
| Des Moines to Deerfield (Illinois) | 299.07 mi (481.30 km) |
| Des Moines to Deerfield Beach (Florida) | 1,304.17 mi (2,098.86 km) |
| Des Moines to Defiance (Ohio) | 479.13 mi (771.09 km) |
| Des Moines to DeForest (Wisconsin) | 245.97 mi (395.85 km) |
| Des Moines to DeKalb (Illinois) | 251.83 mi (405.28 km) |
| Des Moines to Del Aire (California) | 1,446.10 mi (2,327.28 km) |
| Des Moines to Del City (Oklahoma) | 470.97 mi (757.95 km) |
| Des Moines to Del Rio (Texas) | 936.16 mi (1,506.60 km) |
| Des Moines to DeLand (Florida) | 1,108.75 mi (1,784.36 km) |
| Des Moines to Delano (California) | 1,434.79 mi (2,309.07 km) |
