| Des Moines to Darby (Pennsylvania) | 965.41 mi (1,553.68 km) |
| Des Moines to Dardenne Prairie (Missouri) | 246.86 mi (397.29 km) |
| Des Moines to Darien (Illinois) | 290.73 mi (467.88 km) |
| Des Moines to Davenport (Iowa) | 155.35 mi (250.02 km) |
| Des Moines to Davidson (North Carolina) | 807.78 mi (1,299.99 km) |
| Des Moines to Davie (Florida) | 1,312.09 mi (2,111.61 km) |
| Des Moines to Davis (California) | 1,495.10 mi (2,406.13 km) |
| Des Moines to Dayton (Nevada) | 1,369.45 mi (2,203.92 km) |
| Des Moines to Dayton (Ohio) | 508.11 mi (817.73 km) |
| Des Moines to Daytona Beach (Florida) | 1,105.47 mi (1,779.09 km) |
| Des Moines to De Pere (Wisconsin) | 342.13 mi (550.61 km) |
| Des Moines to De Witt (New York) | 899.74 mi (1,447.98 km) |
| Des Moines to Dearborn (Michigan) | 536.46 mi (863.34 km) |
| Des Moines to Dearborn Heights (Michigan) | 533.20 mi (858.11 km) |
| Des Moines to DeBary (Florida) | 1,115.45 mi (1,795.15 km) |
