| Des Moines to Crawfordsville (Indiana) | 366.52 mi (589.85 km) |
| Des Moines to Crest Hill (Illinois) | 284.15 mi (457.29 km) |
| Des Moines to Crestview (Florida) | 843.80 mi (1,357.97 km) |
| Des Moines to Crestwood (Illinois) | 303.27 mi (488.07 km) |
| Des Moines to Crestwood (Missouri) | 269.44 mi (433.63 km) |
| Des Moines to Creve Coeur (Missouri) | 261.59 mi (420.98 km) |
| Des Moines to Crofton (Maryland) | 908.01 mi (1,461.31 km) |
| Des Moines to Crossville (Tennessee) | 603.19 mi (970.74 km) |
| Des Moines to Crowley (Louisiana) | 787.57 mi (1,267.47 km) |
| Des Moines to Crowley (Texas) | 654.71 mi (1,053.66 km) |
| Des Moines to Crown Point (Indiana) | 324.34 mi (521.97 km) |
| Des Moines to Crystal (Minnesota) | 239.75 mi (385.85 km) |
| Des Moines to Crystal Lake (Illinois) | 275.05 mi (442.66 km) |
| Des Moines to Cudahy (California) | 1,435.20 mi (2,309.72 km) |
| Des Moines to Cudahy (Wisconsin) | 308.73 mi (496.86 km) |
