| Des Moines to Cordele (Georgia) | 857.92 mi (1,380.69 km) |
| Des Moines to Corinth (Mississippi) | 534.52 mi (860.23 km) |
| Des Moines to Corinth (Texas) | 612.42 mi (985.60 km) |
| Des Moines to Cornelius (North Carolina) | 805.64 mi (1,296.55 km) |
| Des Moines to Cornelius (Oregon) | 1,490.67 mi (2,399.00 km) |
| Des Moines to Corning (New York) | 851.47 mi (1,370.30 km) |
| Des Moines to Corona (California) | 1,407.58 mi (2,265.29 km) |
| Des Moines to Coronado (California) | 1,429.77 mi (2,300.99 km) |
| Des Moines to Corpus Christi (Texas) | 980.12 mi (1,577.35 km) |
| Des Moines to Corsicana (Texas) | 674.34 mi (1,085.25 km) |
| Des Moines to Cortland (New York) | 895.08 mi (1,440.50 km) |
| Des Moines to Corvallis (Oregon) | 1,503.22 mi (2,419.19 km) |
| Des Moines to Coshocton (Ohio) | 620.27 mi (998.23 km) |
| Des Moines to Costa Mesa (California) | 1,431.64 mi (2,304.00 km) |
| Des Moines to Coto de Caza (California) | 1,417.69 mi (2,281.56 km) |
