| Des Moines to Conyers (Georgia) | 757.56 mi (1,219.18 km) |
| Des Moines to Cookeville (Tennessee) | 574.29 mi (924.24 km) |
| Des Moines to Coolidge (Arizona) | 1,148.39 mi (1,848.15 km) |
| Des Moines to Coon Rapids (Minnesota) | 249.40 mi (401.37 km) |
| Des Moines to Cooper City (Florida) | 1,314.03 mi (2,114.73 km) |
| Des Moines to Coos Bay (Oregon) | 1,556.74 mi (2,505.33 km) |
| Des Moines to Copiague (New York) | 1,051.78 mi (1,692.67 km) |
| Des Moines to Coppell (Texas) | 623.01 mi (1,002.63 km) |
| Des Moines to Copperas Cove (Texas) | 760.64 mi (1,224.14 km) |
| Des Moines to Coral Gables (Florida) | 1,334.65 mi (2,147.91 km) |
| Des Moines to Coral Springs (Florida) | 1,301.83 mi (2,095.09 km) |
| Des Moines to Coral Terrace (Florida) | 1,331.05 mi (2,142.12 km) |
| Des Moines to Coralville (Iowa) | 104.36 mi (167.94 km) |
| Des Moines to Coram (New York) | 1,069.25 mi (1,720.79 km) |
| Des Moines to Corcoran (California) | 1,441.27 mi (2,319.50 km) |
