| Des Moines to Cold Springs (Nevada) | 1,383.23 mi (2,226.10 km) |
| Des Moines to Coldwater (Michigan) | 444.41 mi (715.20 km) |
| Des Moines to Colesville (Maryland) | 890.35 mi (1,432.88 km) |
| Des Moines to College (Alaska) | 2,634.90 mi (4,240.46 km) |
| Des Moines to College Park (Georgia) | 741.64 mi (1,193.55 km) |
| Des Moines to College Park (Maryland) | 895.33 mi (1,440.90 km) |
| Des Moines to College Station (Texas) | 773.70 mi (1,245.15 km) |
| Des Moines to Collegedale (Tennessee) | 646.18 mi (1,039.93 km) |
| Des Moines to Colleyville (Texas) | 630.44 mi (1,014.60 km) |
| Des Moines to Collierville (Tennessee) | 498.11 mi (801.63 km) |
| Des Moines to Collinsville (Illinois) | 276.14 mi (444.40 km) |
| Des Moines to Colonia (New Jersey) | 1,005.10 mi (1,617.55 km) |
| Des Moines to Colonial Heights (Virginia) | 913.48 mi (1,470.10 km) |
| Des Moines to Colonial Park (Pennsylvania) | 880.08 mi (1,416.36 km) |
| Des Moines to Colorado Springs (Colorado) | 616.69 mi (992.47 km) |
