| Des Moines to Cloverleaf (Texas) | 818.88 mi (1,317.86 km) |
| Des Moines to Cloverly (Maryland) | 889.77 mi (1,431.95 km) |
| Des Moines to Clovis (California) | 1,428.08 mi (2,298.27 km) |
| Des Moines to Clovis (New Mexico) | 716.88 mi (1,153.70 km) |
| Des Moines to Clute (Texas) | 872.69 mi (1,404.45 km) |
| Des Moines to Coachella (California) | 1,342.65 mi (2,160.78 km) |
| Des Moines to Coalinga (California) | 1,478.90 mi (2,380.07 km) |
| Des Moines to Coamo (Puerto Rico) | 2,283.67 mi (3,675.21 km) |
| Des Moines to Coatesville (Pennsylvania) | 935.55 mi (1,505.63 km) |
| Des Moines to Cockeysville (Maryland) | 901.93 mi (1,451.52 km) |
| Des Moines to Cocoa (Florida) | 1,163.08 mi (1,871.79 km) |
| Des Moines to Cocoa Beach (Florida) | 1,170.77 mi (1,884.17 km) |
| Des Moines to Coconut Creek (Florida) | 1,303.72 mi (2,098.14 km) |
| Des Moines to Coeur d'Alene (Idaho) | 1,210.33 mi (1,947.83 km) |
| Des Moines to Cohoes (New York) | 1,020.15 mi (1,641.77 km) |
