| Des Moines to Clemson (South Carolina) | 754.59 mi (1,214.40 km) |
| Des Moines to Clermont (Florida) | 1,121.89 mi (1,805.50 km) |
| Des Moines to Cleveland (Mississippi) | 563.30 mi (906.55 km) |
| Des Moines to Cleveland (Ohio) | 616.66 mi (992.42 km) |
| Des Moines to Cleveland (Tennessee) | 646.71 mi (1,040.79 km) |
| Des Moines to Cleveland Heights (Ohio) | 622.51 mi (1,001.83 km) |
| Des Moines to Cliffside Park (New Jersey) | 1,019.28 mi (1,640.37 km) |
| Des Moines to Clifton (Colorado) | 799.94 mi (1,287.38 km) |
| Des Moines to Clifton (New Jersey) | 1,010.07 mi (1,625.56 km) |
| Des Moines to Clinton (Iowa) | 174.79 mi (281.29 km) |
| Des Moines to Clinton (Maryland) | 901.79 mi (1,451.30 km) |
| Des Moines to Clinton (Mississippi) | 661.88 mi (1,065.20 km) |
| Des Moines to Clinton (Utah) | 955.78 mi (1,538.17 km) |
| Des Moines to Clive (Iowa) | 10.12 mi (16.28 km) |
| Des Moines to Cloquet (Minnesota) | 360.08 mi (579.50 km) |
