| Des Moines to Chicago Ridge (Illinois) | 301.18 mi (484.70 km) |
| Des Moines to Chickasha (Oklahoma) | 508.69 mi (818.66 km) |
| Des Moines to Chico (California) | 1,476.95 mi (2,376.92 km) |
| Des Moines to Chicopee (Massachusetts) | 1,080.44 mi (1,738.81 km) |
| Des Moines to Chillicothe (Ohio) | 578.65 mi (931.25 km) |
| Des Moines to Chillum (Maryland) | 893.59 mi (1,438.09 km) |
| Des Moines to Chino (California) | 1,408.52 mi (2,266.80 km) |
| Des Moines to Chino Hills (California) | 1,412.63 mi (2,273.41 km) |
| Des Moines to Chino Valley (Arizona) | 1,121.45 mi (1,804.80 km) |
| Des Moines to Chippewa Falls (Wisconsin) | 257.82 mi (414.92 km) |
| Des Moines to Choctaw (Oklahoma) | 464.90 mi (748.18 km) |
| Des Moines to Chowchilla (California) | 1,449.58 mi (2,332.87 km) |
| Des Moines to Christiansburg (Virginia) | 768.08 mi (1,236.11 km) |
| Des Moines to Chubbuck (Idaho) | 966.65 mi (1,555.67 km) |
| Des Moines to Chula Vista (California) | 1,423.95 mi (2,291.63 km) |
