| Des Moines to Channelview (Texas) | 818.32 mi (1,316.96 km) |
| Des Moines to Chantilly (Virginia) | 871.28 mi (1,402.18 km) |
| Des Moines to Chaparral (New Mexico) | 964.67 mi (1,552.49 km) |
| Des Moines to Chapel Hill (North Carolina) | 875.15 mi (1,408.41 km) |
| Des Moines to Charleston (Illinois) | 319.62 mi (514.38 km) |
| Des Moines to Charleston (South Carolina) | 962.16 mi (1,548.44 km) |
| Des Moines to Charleston (West Virginia) | 671.64 mi (1,080.90 km) |
| Des Moines to Charlotte (North Carolina) | 818.65 mi (1,317.49 km) |
| Des Moines to Charlottesville (Virginia) | 837.86 mi (1,348.41 km) |
| Des Moines to Chaska (Minnesota) | 224.13 mi (360.71 km) |
| Des Moines to Chatham (Illinois) | 243.72 mi (392.23 km) |
| Des Moines to Chattanooga (Tennessee) | 637.82 mi (1,026.48 km) |
| Des Moines to Cheat Lake (West Virginia) | 732.42 mi (1,178.72 km) |
| Des Moines to Chelsea (Alabama) | 685.91 mi (1,103.87 km) |
| Des Moines to Chelsea (Massachusetts) | 1,157.57 mi (1,862.92 km) |
