| Des Moines to Carrollwood (Florida) | 1,123.91 mi (1,808.77 km) |
| Des Moines to Carson (California) | 1,443.05 mi (2,322.36 km) |
| Des Moines to Carson City (Nevada) | 1,380.83 mi (2,222.23 km) |
| Des Moines to Carteret (New Jersey) | 1,009.66 mi (1,624.88 km) |
| Des Moines to Cartersville (Georgia) | 701.29 mi (1,128.61 km) |
| Des Moines to Carthage (Missouri) | 307.90 mi (495.52 km) |
| Des Moines to Cary (Illinois) | 279.21 mi (449.35 km) |
| Des Moines to Cary (North Carolina) | 890.86 mi (1,433.69 km) |
| Des Moines to Casa de Oro-Mount Helix (California) | 1,416.70 mi (2,279.95 km) |
| Des Moines to Casa Grande (Arizona) | 1,160.66 mi (1,867.90 km) |
| Des Moines to Casas Adobes (Arizona) | 1,149.66 mi (1,850.21 km) |
| Des Moines to Cascades (Virginia) | 871.01 mi (1,401.75 km) |
| Des Moines to Casper (Wyoming) | 655.74 mi (1,055.31 km) |
| Des Moines to Casselberry (Florida) | 1,127.97 mi (1,815.30 km) |
| Des Moines to Castaic (California) | 1,441.01 mi (2,319.08 km) |
