| Des Moines to Candler-McAfee (Georgia) | 743.96 mi (1,197.29 km) |
| Des Moines to Caño Martin Peña (Puerto Rico) | 2,277.68 mi (3,665.57 km) |
| Des Moines to Cañon City (Colorado) | 650.72 mi (1,047.24 km) |
| Des Moines to Canóvanas (Puerto Rico) | 2,287.21 mi (3,680.91 km) |
| Des Moines to Canton (Georgia) | 708.71 mi (1,140.55 km) |
| Des Moines to Canton (Illinois) | 198.57 mi (319.57 km) |
| Des Moines to Canton (Mississippi) | 650.56 mi (1,046.98 km) |
| Des Moines to Canton (Ohio) | 638.21 mi (1,027.11 km) |
| Des Moines to Canyon (Texas) | 639.58 mi (1,029.31 km) |
| Des Moines to Canyon Lake (California) | 1,398.35 mi (2,250.42 km) |
| Des Moines to Canyon Lake (Texas) | 848.84 mi (1,366.07 km) |
| Des Moines to Cape Coral (Florida) | 1,224.31 mi (1,970.33 km) |
| Des Moines to Cape Girardeau (Missouri) | 365.17 mi (587.68 km) |
| Des Moines to Carbondale (Illinois) | 353.79 mi (569.37 km) |
| Des Moines to Carlisle (Pennsylvania) | 860.94 mi (1,385.55 km) |
