| Des Moines to Cadillac (Michigan) | 453.76 mi (730.26 km) |
| Des Moines to Caguas (Puerto Rico) | 2,288.80 mi (3,683.46 km) |
| Des Moines to Cahokia (Illinois) | 275.80 mi (443.86 km) |
| Des Moines to Calabasas (California) | 1,453.94 mi (2,339.90 km) |
| Des Moines to Caldwell (Idaho) | 1,176.95 mi (1,894.12 km) |
| Des Moines to Caledonia (Wisconsin) | 305.48 mi (491.63 km) |
| Des Moines to Calera (Alabama) | 694.31 mi (1,117.38 km) |
| Des Moines to Calexico (California) | 1,347.56 mi (2,168.69 km) |
| Des Moines to Calhoun (Georgia) | 679.09 mi (1,092.90 km) |
| Des Moines to California (Maryland) | 932.86 mi (1,501.29 km) |
| Des Moines to California City (California) | 1,381.56 mi (2,223.41 km) |
| Des Moines to Callaway (Florida) | 908.89 mi (1,462.71 km) |
| Des Moines to Calumet City (Illinois) | 313.09 mi (503.87 km) |
| Des Moines to Calverton (Maryland) | 893.33 mi (1,437.68 km) |
| Des Moines to Camano (Washington) | 1,474.90 mi (2,373.62 km) |
