| Des Moines to Blue Island (Illinois) | 306.28 mi (492.92 km) |
| Des Moines to Blue Springs (Missouri) | 180.29 mi (290.14 km) |
| Des Moines to Bluffdale (Utah) | 956.56 mi (1,539.44 km) |
| Des Moines to Bluffton (Indiana) | 442.47 mi (712.09 km) |
| Des Moines to Bluffton (South Carolina) | 951.49 mi (1,531.28 km) |
| Des Moines to Blythe (California) | 1,270.07 mi (2,043.98 km) |
| Des Moines to Blytheville (Arkansas) | 437.77 mi (704.52 km) |
| Des Moines to Boca Raton (Florida) | 1,300.75 mi (2,093.35 km) |
| Des Moines to Boerne (Texas) | 863.20 mi (1,389.18 km) |
| Des Moines to Bogalusa (Louisiana) | 774.12 mi (1,245.83 km) |
| Des Moines to Boiling Springs (South Carolina) | 774.21 mi (1,245.97 km) |
| Des Moines to Boise (Idaho) | 1,155.57 mi (1,859.71 km) |
| Des Moines to Bolingbrook (Illinois) | 284.54 mi (457.92 km) |
| Des Moines to Bolivar (Missouri) | 274.26 mi (441.38 km) |
| Des Moines to Bon Air (Virginia) | 897.69 mi (1,444.69 km) |
