| Des Moines to Ashtabula (Ohio) | 660.40 mi (1,062.82 km) |
| Des Moines to Ashwaubenon (Wisconsin) | 343.57 mi (552.92 km) |
| Des Moines to Aspen Hill (Maryland) | 885.77 mi (1,425.50 km) |
| Des Moines to Astoria (Oregon) | 1,527.40 mi (2,458.12 km) |
| Des Moines to Atascadero (California) | 1,515.69 mi (2,439.27 km) |
| Des Moines to Atascocita (Texas) | 805.99 mi (1,297.12 km) |
| Des Moines to Atchison (Kansas) | 160.32 mi (258.00 km) |
| Des Moines to Athens (Alabama) | 591.90 mi (952.56 km) |
| Des Moines to Athens (Georgia) | 767.25 mi (1,234.76 km) |
| Des Moines to Athens (Ohio) | 624.30 mi (1,004.72 km) |
| Des Moines to Athens (Tennessee) | 644.00 mi (1,036.41 km) |
| Des Moines to Athens (Texas) | 658.76 mi (1,060.18 km) |
| Des Moines to Atlanta (Georgia) | 736.49 mi (1,185.27 km) |
| Des Moines to Atlantic Beach (Florida) | 1,031.28 mi (1,659.69 km) |
| Des Moines to Atlantic City (New Jersey) | 1,016.06 mi (1,635.20 km) |
