| Des Moines to Arroyo Grande (California) | 1,520.86 mi (2,447.59 km) |
| Des Moines to Artesia (California) | 1,433.23 mi (2,306.56 km) |
| Des Moines to Artesia (New Mexico) | 845.71 mi (1,361.04 km) |
| Des Moines to Artondale (Washington) | 1,476.31 mi (2,375.89 km) |
| Des Moines to Arvada (Colorado) | 615.84 mi (991.10 km) |
| Des Moines to Arvin (California) | 1,429.22 mi (2,300.11 km) |
| Des Moines to Asbury Lake (Florida) | 1,033.84 mi (1,663.80 km) |
| Des Moines to Asbury Park (New Jersey) | 1,025.58 mi (1,650.52 km) |
| Des Moines to Ashburn (Virginia) | 867.07 mi (1,395.41 km) |
| Des Moines to Asheboro (North Carolina) | 846.00 mi (1,361.50 km) |
| Des Moines to Asheville (North Carolina) | 726.17 mi (1,168.66 km) |
| Des Moines to Ashland (California) | 1,533.08 mi (2,467.25 km) |
| Des Moines to Ashland (Kentucky) | 618.30 mi (995.06 km) |
| Des Moines to Ashland (Ohio) | 588.61 mi (947.27 km) |
| Des Moines to Ashland (Oregon) | 1,489.71 mi (2,397.45 km) |
