| Des Moines to Alderwood Manor (Washington) | 1,462.48 mi (2,353.63 km) |
| Des Moines to Aldine (Texas) | 811.67 mi (1,306.25 km) |
| Des Moines to Alexander City (Alabama) | 730.97 mi (1,176.38 km) |
| Des Moines to Alexandria (Louisiana) | 713.10 mi (1,147.62 km) |
| Des Moines to Alexandria (Minnesota) | 310.23 mi (499.26 km) |
| Des Moines to Alexandria (Virginia) | 891.13 mi (1,434.13 km) |
| Des Moines to Algonquin (Illinois) | 275.41 mi (443.23 km) |
| Des Moines to Alhambra (California) | 1,428.81 mi (2,299.45 km) |
| Des Moines to Alice (Texas) | 987.26 mi (1,588.85 km) |
| Des Moines to Aliso Viejo (California) | 1,425.40 mi (2,293.96 km) |
| Des Moines to Allen (Texas) | 608.39 mi (979.11 km) |
| Des Moines to Allen Park (Michigan) | 536.46 mi (863.35 km) |
| Des Moines to Allendale (Michigan) | 403.42 mi (649.25 km) |
| Des Moines to Allentown (Pennsylvania) | 945.10 mi (1,521.00 km) |
| Des Moines to Alliance (Ohio) | 650.02 mi (1,046.11 km) |
