| Des Moines to Alachua (Florida) | 1,024.80 mi (1,649.26 km) |
| Des Moines to Alafaya (Florida) | 1,140.26 mi (1,835.08 km) |
| Des Moines to Alameda (California) | 1,539.26 mi (2,477.20 km) |
| Des Moines to Alamo (California) | 1,524.21 mi (2,452.98 km) |
| Des Moines to Alamo (Texas) | 1,093.99 mi (1,760.61 km) |
| Des Moines to Alamogordo (New Mexico) | 905.04 mi (1,456.52 km) |
| Des Moines to Albany (California) | 1,538.34 mi (2,475.71 km) |
| Des Moines to Albany (Georgia) | 865.37 mi (1,392.68 km) |
| Des Moines to Albany (New York) | 1,015.82 mi (1,634.81 km) |
| Des Moines to Albany (Oregon) | 1,494.13 mi (2,404.57 km) |
| Des Moines to Albemarle (North Carolina) | 841.94 mi (1,354.96 km) |
| Des Moines to Albert Lea (Minnesota) | 144.42 mi (232.42 km) |
| Des Moines to Albertville (Alabama) | 645.77 mi (1,039.26 km) |
| Des Moines to Albuquerque (New Mexico) | 834.51 mi (1,343.01 km) |
| Des Moines to Alcoa (Tennessee) | 654.03 mi (1,052.56 km) |
