| Des Moines to Abilene (Texas) | 714.50 mi (1,149.88 km) |
| Des Moines to Accokeek (Maryland) | 898.48 mi (1,445.96 km) |
| Des Moines to Acworth (Georgia) | 711.75 mi (1,145.46 km) |
| Des Moines to Ada (Oklahoma) | 498.64 mi (802.49 km) |
| Des Moines to Addison (Illinois) | 289.77 mi (466.34 km) |
| Des Moines to Addison (Texas) | 620.86 mi (999.18 km) |
| Des Moines to Adelanto (California) | 1,377.62 mi (2,217.07 km) |
| Des Moines to Adelphi (Maryland) | 893.61 mi (1,438.13 km) |
| Des Moines to Adrian (Michigan) | 493.46 mi (794.15 km) |
| Des Moines to Affton (Missouri) | 271.57 mi (437.05 km) |
| Des Moines to Agoura Hills (California) | 1,458.15 mi (2,346.66 km) |
| Des Moines to Aguadilla (Puerto Rico) | 2,231.74 mi (3,591.63 km) |
| Des Moines to Aiken (South Carolina) | 854.40 mi (1,375.02 km) |
| Des Moines to Akron (Ohio) | 627.64 mi (1,010.10 km) |
| Des Moines to Alabaster (Alabama) | 686.41 mi (1,104.67 km) |
